BASKET
HELP
Product details for Cyclin D1 (Human) antibody
Cyclin D1 (Human) antibody
Overview
|
|
| Antigen: | Cyclin D1 |
| Antibody Type: | Polyclonal |
| Application: | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Reactivity: | Human |
| Host: | Rabbit |
| Quantity: | |
| Price: | 559,43 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN97962 |
| Availability: | 7 days until shipment |
Additional Information: Cyclin D1 (Human) antibody
| Antigen | Cyclin D1 |
| Immunogen | A synthetic peptide from c-terminus of human cyclin D1. |
| Reactivity | Human |
| Antibody Type | Polyclonal |
| Format | Ig Fraction, Purified |
| Host | Rabbit |
| Specificity | This antibody reacts with a 36 kD protein. Cyclin D1 or PRAD-1 or bcl-1 is one of the key cell cycle regulators and functions in association with cdk4 and / or cdk6 by phosphorylating the Rb protein. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL). This antibody reacts with mouse and rat. |
Application Details: Cyclin D1 (Human) antibody
| Application | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Application Notes | Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:200 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Breast carcinoma, mantle cell lymphoma. Cellular localization: Nuclear |
| Buffer | Purified immunoglobulin fraction of rabbit antiserum against Cyclin D1 containing sodium azide as preservative. |
| Storage | Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label. |
| Research Area | Cell Cycle |
| Restrictions | For Research Use only |
Images: Cyclin D1 (Human) antibody
|
Formalin fixed paraffin embedded human Mantle cell lymphoma stained with Cyclin D1 antibody |
Product variants
External Information: Cyclin D1 (Human) antibody
| Google Scholar | Find more references for antigen Cyclin D1 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Cyclin D1 (Bioinformatic Harvester (EMBL)) |
browse antibodies by
Antigens
Secondary Antibodies
Research areas
Clones
Hosts
Applications
Reactivity
Supplier
Antigens
Secondary Antibodies
Research areas
Clones
Hosts
Applications
Reactivity
Supplier
