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产品详细信息： D type cyclin (encoded by KSV) antibody
D type cyclin (encoded by KSV) antibody
概述
| 抗原: | D type cyclin (encoded by KSV) |
| 抗体类型: | 单克隆抗体 |
| 应用范围: | Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB) |
| 抗体来源: | Rat |
| 规格: | |
| 价格: | 2.675,50 ¥ (加上运费和增值税, Invoice in EUR) |
| 货号: | ABIN145114 |
| 发货时间: | 7 to 10 days until shipment |
详细信息: D type cyclin (encoded by KSV) antibody
| 抗原 | D type cyclin (encoded by KSV) |
| 免疫原 | Recombinant fusion protein produced from a clone from KSV. |
| 抗体类型 | 单克隆抗体 |
| 状态 | Liquid |
| 抗体同种型 | IgG »相配的二抗 |
| 描述 | This protein was identified by the interaction with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported. |
| 克隆 | 94B |
| 抗体来源 | Rat |
使用细节: D type cyclin (encoded by KSV) antibody
| 应用范围 | Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB) |
| 应用备注 | IF: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 30 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| 浓度 | 1 mg/ml |
| 纯度 | Protein A purified |
| 缓冲液 | Preservative: NoneConstituents: PBS |
| 贮藏 | Store at 4 C. Aliquot and store at -20 C long-term. |
| 限制 | For research use only |
