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Produktdetails für  D type cyclin (encoded by KSV) antibody

D type cyclin (encoded by KSV) antibody

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Antigen: D type cyclin (encoded by KSV)
Antikörper-Typ: Monoklonal
Applikation: Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
Wirt: Rat
Menge: 100 µg (1 mg/ml)
Preis: 291,00 €   (Zzgl. Versandkosten und MWSt)
Bestellnummer: ABIN145114
Verfügbarkeit: 7 to 10 days until shipment
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Produktbeschreibung:  D type cyclin (encoded by KSV) antibody

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Antigen D type cyclin (encoded by KSV)
Immunogen Recombinant fusion protein produced from a clone from KSV.
Antikörper-Typ Monoklonal
Format Liquid
Isotyp IgG »Passende Sekundärantikörper
Beschreibung This protein was identified by the interaction with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.
Klon 94B
Wirt Rat

Anwendungen:  D type cyclin (encoded by KSV) antibody

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Applikation Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
Applikationshinweise IF: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 30 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Konzentration 1 mg/ml
Reinheit Protein A purified
Buffer Preservative: NoneConstituents: PBS
Lagerung Store at 4 C. Aliquot and store at -20 C long-term.
Beschränkungen For research use only

Weitere Informationen:  D type cyclin (encoded by KSV) antibody

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