BASKET
HELP
Product details for D4 GDI (Human) antibody
D4 GDI (Human) antibody
Overview
| Antigen: | D4 GDI |
| Antibody Type: | Polyclonal |
| Application: | Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Bovine |
| Host: | Rabbit |
| Quantity: | |
| Price: | 335,80 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN149977 |
| Availability: | 7 to 10 days until shipment |
Additional Information: D4 GDI (Human) antibody
| Antigen | D4 GDI |
| Immunogen | Synthetic peptide: KAPEPHVEEDDDDELDSKC conjugated to KLH, corresponding to amino acids 4-21 of Human D4 GDI. |
| Reactivity | Human, Bovine |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | GDP-dissociation inhibitors or GDIs, modulate the activation of GTPases, and may also be involved in the cellular compartmentalization of GTPases. GDIs modulate GTPase activity by binding to small G Proteins, and regulating GDP/GTP exchange. This family of proteins includes Rho-GDI (GDI-1), D4 GDI (GDI-2) and Rho-GDI-3 (GDI-3). Rho-GDI and D4 GDI are both localized in cystol. RhoGDI and GDI/D4 are both members of the Rho subfamily of GTPases. These two proteins are highly homologous, differing primarily in the first 25 amino acids of the N-terminus. D4 GDI has been described as a Caspase 3 (CPP32/YAMA/Apopain) substrate during Fas-induced apoptosis and is located in the cytosol. |
| Host | Rabbit |
| Specificity | Ab12427 specifically reacts with D4 GDI and does not recognize Rho-GDI or GDI-3. |
Application Details: D4 GDI (Human) antibody
| Application | Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | IP: 4 ug is recommended to immunoprecipitate D4 GDI from 500 ug of Jurkat RIPA lysate. WB: Use at a concentration of 0.5-1 ug/ml. THis concentration is recommended for blotting using RIPA lysates from human A431, HL-60 and Jurkat cells, anti-rabbit IgG-peroxidase conjugate and a chemiluminescent detection system. Predicted molecular weight: 28 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 0.7 mg/ml |
| Purity | Protein A purified |
| Buffer | Preservative: 0.035% Sodium AzideConstituents: 30% Glycerol, 0.105M Sodium Chloride, 0.07M Tris-glycine. pH 7.4 |
| Restrictions | For research use only |
Product variants
| D4 GDI (Human) antibody (Format: Liquid, Quantity: 500 µl) |
| D4 GDI (Human) antibody (Quantity: 7 ml) |
External Information: D4 GDI (Human) antibody
| Google Scholar | Find more references for antigen D4 GDI on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen D4 GDI (Bioinformatic Harvester (EMBL)) |
browse antibodies by
Antigens
Secondary Antibodies
Research areas
Clones
Hosts
Applications
Reactivity
Supplier
Antigens
Secondary Antibodies
Research areas
Clones
Hosts
Applications
Reactivity
Supplier
