DAP5 (Human) antibody

Overview

Antigen:	DAP5
Antibody Type:	Polyclonal
Application:	Western Blotting (WB)
Reactivity:	Human, Mouse (Murine), Rat
Host:	Rabbit
Quantity:	100 µg
Price:	361,63 $ (Plus shipping costs , $13.59 dry ice fee and VAT, Invoice in EUR)
Order number:	ABIN130462
Availability:	7 to 10 days until shipment

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Additional Information: DAP5 (Human) antibody

Antigen	DAP5
Reactivity	Human, Mouse (Murine), Rat
Antibody Type	Polyclonal
Format	Liquid
Isotype	IgG, Ig »Matching secondary antibodies
Description	Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to eukaryotic translation initiation factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
Host	Rabbit
Specificity	This antibody reacts with DAP5 protein in human, mouse, and rat. The antibody detects the 97 kDa DAP5. It does not cross react with other DAP family members or with eIF4G.

Application Details: DAP5 (Human) antibody

Application	Western Blotting (WB)
Application Notes	Suitable for use in Western blotting analysis (1 - 2 µg/ml).
Buffer	Supplied as 100 µg (0.2 mg/ml) affinity-purified rabbit anti-DAP5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Restrictions	For Research Use Only

Publications: DAP5 (Human) antibody

Publications

Imataka, Olsen, Sonenberg:
"A new translational regulator with homology to eukaryotic translation initiation factor 4G."
In: The EMBO journal , Vol. 16, Issue 4, pp. 817-25, 1997/01 (PubMed)

Levy-Strumpf, Kimchi:
"Death associated proteins (DAPs): from gene identification to the analysis of their apoptotic and tumor suppressive functions."
In: Oncogene , Vol. 17, Issue 25, pp. 3331-40, 1999/01 (PubMed)

External Information: DAP5 (Human) antibody

Google Scholar	Find more references for antigen DAP5 on Google Scholar™
EMBL Harvester	Search human, mouse or rat genome for antigen DAP5 (Bioinformatic Harvester (EMBL))