DAP5 (Human) antibody

Overview

Antigen:	DAP5
Antibody Type:	Polyclonal
Application:	Western Blotting (WB)
Reactivity:	Human, Mouse (Murine), Rat
Host:	Rabbit
Quantity:	50 µg (0.5 mg/ml)
Price:	335,80 $ (Plus shipping costs and VAT, Invoice in EUR)
Order number:	ABIN150546
Availability:	7 to 10 days until shipment

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Additional Information: DAP5 (Human) antibody

Antigen	DAP5
Immunogen	Available on request.
Reactivity	Human, Mouse (Murine), Rat
Antibody Type	Polyclonal
Isotype	IgG »Matching secondary antibodies
Description	Death Associated Protein 5 (DAP 5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP 5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP 5 is cleaved at Asp790. The C-terminal truncated form of DAP 5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
Host	Rabbit
Specificity	This antibody recognizes the 97 kDa DAP 5. It does not cross-react with other DAP family members or with eIF4G.

Application Details: DAP5 (Human) antibody

Application	Western Blotting (WB)
Application Notes	WB: Use at a concentration of 1-2 ug/ml. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Concentration	0.5 mg/ml
Purity	Immunogen affinity purified
Buffer	PBS pH7.2 with 50% glycerol, 1% BSA and 0.02% sodium azide
Storage	Store at -20 C. For long term storage, aliquot and refreeze at -70 C. Avoid repeated freeze/defrost cycles
Restrictions	For research use only

Publications: DAP5 (Human) antibody

Publications

Imataka, Olsen, Sonenberg:
"A new translational regulator with homology to eukaryotic translation initiation factor 4G."
In: The EMBO journal , Vol. 16, Issue 4, pp. 817-25, 1997/01 (PubMed)

Enser:
"Desaturation of stearic acid by liver and adipose tissue from obese-hyperglycaemic mice (ob/ob)."
In: The Biochemical journal , Vol. 148, Issue 3, pp. 551-5, 1976/01 (PubMed)

External Information: DAP5 (Human) antibody

Google Scholar	Find more references for antigen DAP5 on Google Scholar™
EMBL Harvester	Search human, mouse or rat genome for antigen DAP5 (Bioinformatic Harvester (EMBL))