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Product details for DARPP-32 (Human) antibody
DARPP-32 (Human) antibody
Overview
| Antigen: | DARPP-32 |
| Antibody Type: | Polyclonal |
| Application: | Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 475,82 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN152638 |
| Availability: | Ships in 7 to 10 days |
Additional Information: DARPP-32 (Human) antibody
| Antigen | DARPP-32 |
| Immunogen | Peptide corresponding to amino acid residues from the N-terminus region of DARPP-32,conjugated to keyhole limpet hemocyanin (KLH). |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Polyclonal |
| Format | Aff - Purified |
| Description | DARPP-32 is a dopamine (DA) and cAMP-regulated ~32k phosphoprotein that isassociated with dopaminoceptive neurons. The protein inhibits Protein Phosphatase Iwhen it is phosphorylated on Thr34. In contrast, when DARPP-32 is phosphorylated onThr75 the protein acts as an inhibitor of PKA. Phosphorylation of DARPP- 2 is thoughtto play a critical role in the regulation of dopaminergic neurotransmission. In addition,the activity of DARPP-32 is also thought to play important roles in the actions of alcohol,caffeine and Prozac® (1-5). Synonyms: DARPP 32 antibody, DARPP32 antibody, Dopamine- and cAMP-regulated neuronalphosphoprotein antibody |
| Host | Rabbit |
| Specificity | Human, mouse, and rat based on 100% antigen sequence homology. |
Application Details: DARPP-32 (Human) antibody
| Application | Western Blotting (WB) |
| Application Notes | WB - 1:1,000*The investigator should determine the optimal working dilution for a specific application. This antibody has been tested in Western blot on rat brain hippocampal lysate, detectinga band ~32 kDa. No other applications have been tested.Recommended Starting |
| Buffer | 0.1 ml of affinity purified rabbit sera. Concentration is unknown. Adequate amount ofmaterial to conduct 10-mini Western blots. 10 mM Hepes (pH7.5), 150 mM NaCl, 100 ug/ml BSA and 50% glycerol |
| Storage | Store at -20 degrees C. Stable for 1 year. |
| Restrictions | For Research Use only |
External Information: DARPP-32 (Human) antibody
| Google Scholar | Find more references for antigen DARPP-32 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen DARPP-32 (Bioinformatic Harvester (EMBL)) |
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