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Product details for DEDAF (Human) antibody
DEDAF (Human) antibody
Overview
| Antigen: | DEDAF |
| Antibody Type: | Polyclonal |
| Application: | Immunofluorescence (IF), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 335,80 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN148780 |
| Availability: | 7 to 10 days until shipment |
Additional Information: DEDAF (Human) antibody
| Antigen | DEDAF |
| Immunogen | Synthetic peptide: TPKGDMSAVNDESF, corresponding to amino acids 215-228 of Human DEDAF. |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. Several molecules including caspases and adaptor FADD contain DEDs. A novel protein that interacts with DED of caspase 8 and 10, and FADD was identified recently and designated DEDAF for DED associated factor. DEDAF is identical to the transcriptional repressor RYBP. DEDAF/RYBP is expressed in multiple tissues and cell lines. DEDAF interacts with FADD and augments the formation of CD95/FADD/capase 8 complexes at the cell membrane, and interacts with DED-containing DNA biding protein (DEDD) in the nucleus indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis. |
| Host | Rabbit |
Application Details: DEDAF (Human) antibody
| Application | Immunofluorescence (IF), Western Blotting (WB) |
| Application Notes | IF: Use at a concentration of 1 ug/ml. WB: Use at a concentration of 0.5-1.0 ug/ml. Detects a band of approximately 32 kDa. Can be blocked with GTX26097 DEDAF peptide (human) . Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 0.5 mg/ml |
| Purity | Immunogen affinity purified |
| Buffer | Preservative: 0.02% Sodium AzideConstituents: PBS |
| Restrictions | For research use only |
External Information: DEDAF (Human) antibody
| Google Scholar | Find more references for antigen DEDAF on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen DEDAF (Bioinformatic Harvester (EMBL)) |
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