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Product details for  DEDAF (Human) antibody
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DEDAF (Human) antibody

Overview

Antigen: DEDAF
Antibody Type: Polyclonal
Application: Western Blotting (WB)
Reactivity: Human, Mouse (Murine), Rat
Host: Rabbit
Quantity: 50 µg (0.5 mg/ml) (Product variants)
Price: 335,80 $   (Plus shipping costs and VAT, Invoice in EUR)
Order number: ABIN150791
Availability: 7 to 10 days until shipment
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Additional Information:  DEDAF (Human) antibody

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Antigen DEDAF
Immunogen Available on request
Reactivity Human, Mouse (Murine), Rat
Antibody Type Polyclonal
Isotype IgG »Matching secondary antibodies
Description Cell death signal are transduced by Death Domain (DD), Death Effector Domain (DED), and Caspase Recruitment Domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10, and FADD was recently identified and designated DEDAF (for DED associated factor). DEDAF is identical to the transcriptional repressor RYBP. DEDAF interacts with FADD and augments the formation of CD95/FADD/caspase-8 complexes at the cytoplasm. DEDAF also interacts with DED-containing DNA binding protein (DEDD) in the nucleus, indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.
Host Rabbit
Specificity This antibody detects ~32kDa DEDAF.

Application Details:  DEDAF (Human) antibody

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Application Western Blotting (WB)
Application Notes WB: Use at a concentration of 1.0 ug/ml. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Concentration 0.5 mg/ml
Purity Immunogen affinity purified
Buffer PBS pH7.2 with 50% glycerol, 1% BSA and 0.02% sodium azide
Storage Store at -20 C. For long term storage, aliquot and refreeze at -70 C. Avoid repeated freeze/defrost cycles
Restrictions For research use only

Publications:  DEDAF (Human) antibody

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Publications Kawai, Nomura, Hoshino et al.:
"Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity."
In: Oncogene , Vol. 18, Issue 23, pp. 3471-80, 1999/01 (PubMed)

Lefkowitz:
"Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists."
In: Biochemical pharmacology , Vol. 24, Issue 18, pp. 1651-8, 1976/01 (PubMed)

External Information:  DEDAF (Human) antibody

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Google Scholar Find more references for antigen DEDAF on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen DEDAF (Bioinformatic Harvester (EMBL))