DEDD2 antibody

Übersicht

Antigen	DEDD2
Antikörper-Typ	Polyklonal
Format	Liquid
Beschreibung	A novel Death Effector Domain-containing protein, DEDD2, is closest in amino acid sequence homology to Death Effector Domain-containing DNA-binding protein, DEDD. DEDD2 is expressed widely in adult human tissues with highest levels in liver, kidney and peripheral blood leukocytes. DEDD2 interacts with FLIP, but not with FADD or Caspase 8. Over-expression of DEDD2 induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas(CD95/APO-1), TRAIL(Apo2L), or FADD. These findings suggest that DEDD2 is involved in the regulation of nuclear events mediated by the extrinsic apoptosis pathway.
Wirt	Rabbit
Spezifität	Reacts with residues 144-129 of the DEDD2 protein.

Applikation	ELISA, Western Blotting (WB)
Applikationshinweise	Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
Reinheit	Serum
Buffer	100 ul serum containing 0.02% sodium azide.
Lagerung	Maintain at +2-8 C for 3 months or at -20 C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.
Beschränkungen	For research use only

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