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Détail du produit pour DEDD2 antibody
DEDD2 antibody
Aperçu
| Antigène: | DEDD2 |
| Type anticorps: | Polyclonal |
| Application: | ELISA, Western Blotting (WB) |
| Hôte: | Rabbit |
| Quantité: | |
| Prix: | 260,00 € (Plus frais de livraison et TVA) |
| Numéro de commande: | ABIN141188 |
| Disponibilité: | 7 to 10 days until shipment |
Description du produit: DEDD2 antibody
| Antigène | DEDD2 |
| Type anticorps | Polyclonal |
| Format | Liquid |
| Description | A novel Death Effector Domain-containing protein, DEDD2, is closest in amino acid sequence homology to Death Effector Domain-containing DNA-binding protein, DEDD. DEDD2 is expressed widely in adult human tissues with highest levels in liver, kidney and peripheral blood leukocytes. DEDD2 interacts with FLIP, but not with FADD or Caspase 8. Over-expression of DEDD2 induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas(CD95/APO-1), TRAIL(Apo2L), or FADD. These findings suggest that DEDD2 is involved in the regulation of nuclear events mediated by the extrinsic apoptosis pathway. |
| Hôte | Rabbit |
| Specificité | Reacts with residues 144-129 of the DEDD2 protein. |
Applications: DEDD2 antibody
| Application | ELISA, Western Blotting (WB) |
| Indications d'application | Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry. |
| Pureté | Serum |
| Buffer | 100 ul serum containing 0.02% sodium azide. |
| Stock | Maintain at +2-8 C for 3 months or at -20 C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles. |
| Restrictions | For research use only |
Informations supplémentaires: DEDD2 antibody
| Google Scholar | Trouver des références supplémentaires pour antigène DEDD2 sur Google Scholar™ |
| EMBL Harvester | Recherche humain, souris ou rat génome pour antigène DEDD2 (Bioinformatic Harvester (EMBL)) |
