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Product details for DIAPH1 (Human) antibody
DIAPH1 (Human) antibody
Overview
| Antigen: | DIAPH1 |
| Antibody Type: | Polyclonal |
| Application: | Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine) |
| Host: | Rabbit |
| Quantity: | |
| Price: | 335,80 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN150119 |
| Availability: | 7 to 10 days until shipment |
Additional Information: DIAPH1 (Human) antibody
| Antigen | DIAPH1 |
| Immunogen | Synthetic peptide, which represents a portion of the human DIAPH1 encoded within exon 1 (LocusLink ID 1729). |
| Reactivity | Human, Mouse (Murine) |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | DIAPH1 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity). In hearing it may play a role in the regulation of actin polymerization in hair cells. |
| Host | Rabbit |
Application Details: DIAPH1 (Human) antibody
| Application | Western Blotting (WB) |
| Application Notes | WB: Use at a dilution of 1/10000-1/30000. Detects a band of approximately 200 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 1 mg/ml |
| Purity | Immunogen affinity purified |
| Buffer | Preservative: 0.1% Sodium AzideConstituents: Tris-citrate/phosphate. pH 7-8 |
| Restrictions | For research use only |
External Information: DIAPH1 (Human) antibody
| Google Scholar | Find more references for antigen DIAPH1 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen DIAPH1 (Bioinformatic Harvester (EMBL)) |
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