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Product details for DNA Ligase I (Human) antibody
DNA Ligase I (Human) antibody
Overview
| Antigen: | DNA Ligase I |
| Antibody Type: | Monoclonal |
| Application: | ELISA, Western Blotting (WB) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 395,61 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN140104 |
| Availability: | 7 to 10 days until shipment |
Additional Information: DNA Ligase I (Human) antibody
| Antigen | DNA Ligase I |
| Immunogen | Full length native protein (purified) (Cow) |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | Eukaryotic DNA ligases are ATP-dependent enzymes that catalyse the joining of single and double-strand DNA breaks, which is an essential final step in DNA replication, recombination and repair. Four biochemically distinct DNA ligases, termed ligases I-IV, have been identified in mammalian cells. DNA ligase I is functionally homologous to the DNA ligase encoded by the Saccharomyces cerevisiae Cdc9 gene. The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is due to DNA ligase I. A combination of DNA polymerase epsilon, PCNA, replication factor C, replication protein A, and DNA ligase I is well-suited to the task of creating nucleotide excision repair patches. |
| Clone | 1A9 |
| Host | Mouse |
Application Details: DNA Ligase I (Human) antibody
| Application | ELISA, Western Blotting (WB) |
| Application Notes | ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 101 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | Batch Dependent |
| Purity | IgG fraction |
| Buffer | Phosphate-buffered saline |
| Storage | Keep as concentrated solution. Store at 4?C short term. For extended storage aliquot and store at -20?C or below. Avoid freeze-thaw cycles. |
| Research Area | DNA/RNA |
| Restrictions | For research use only |
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