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Product details for Dnmt1 (Human) antibody
Dnmt1 (Human) antibody
Overview
| Antigen: | DNA Methyltransferase 1 (Dnmt1) |
| Antibody Type: | Polyclonal |
| Application: | Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine) |
| Host: | Rabbit |
| Quantity: | |
| Price: | 462,23 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN151856 |
| Availability: | Ships in 7 to 10 days |
Additional Information: Dnmt1 (Human) antibody
| Antigen | DNA Methyltransferase 1 (Dnmt1) |
| Immunogen | Synthetic peptide representing a portion of human DNA (cytosine-5-)methyltransferase1 encoded within exon 25 (LocusLink ID 1786). |
| Reactivity | Human, Mouse (Murine) |
| Antibody Type | Polyclonal |
| Format | Purified |
| Description | Inactivation of tumor suppressor genes is a key component of the development of allcommon forms of human cancers. Aberrant methylation may contribute to many of thechanges, both physiological and pathological, associated with aging, including tumordevelopment. Hypermethylation of CpG island-containing promoters is associated withthe inactivation of genes important to tumor angiogenesis and progression. DNAmethytransferase (DNMT1) is necessary for the maintenance of the methylationprocess. Synonyms: DNMT-1 antibody, DNMT 1 antibody, DNMT antibody, DNA9cytosine-5-)-methylatransferase 1 antibody, MCMT antibody, DNA MTase Mmu1antibody, DNA methyltransferase M.HsaI antibody |
| Host | Rabbit |
| Specificity | This antibody is specific to human DNMT1. ABIN151856 can be used to detect DNMT1 in human. Reactivity in mouse is likely basedon similarity of sequence between the mouse ortholog and the peptide used for thisantibody. |
Application Details: Dnmt1 (Human) antibody
| Application | Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | This antibody can be used for Western blot and immunoprecipitation. Other applicationshave not been tested. *Suggested Working Dilution: Western blot: 1:1,000-1:10,000 Immunoprecipitation: 2-4 ug/mg lysateImmunohistochemistry: not tested*Optimal working dilutions should be determined experimentally by the investigator. Positive Control:HeLa nuclear lysates. |
| Concentration | 1 mg/ml |
| Buffer | 0.1 ml of affinity purified DNMT1. Tris-citrate/phosphate pH 7-8 containing 0.1% sodium azide. |
| Storage | Store at 4°C. |
| Research Area | DNA/RNA |
| Restrictions | For Research Use only |
Product variants
External Information: Dnmt1 (Human) antibody
| Google Scholar | Find more references for antigen DNA Methyltransferase 1 (Dnmt1) on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen DNA Methyltransferase 1 (Dnmt1) (Bioinformatic Harvester (EMBL)) |
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