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Product details for Dnmt3b (Human) antibody
Dnmt3b (Human) antibody
Overview
| Antigen: | DNA Methyltransferase 3b (Dnmt3b) |
| Antibody Type: | Polyclonal |
| Application: | ChIP, Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine) |
| Host: | Rabbit |
| Quantity: | |
| Price: | 475,82 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN152675 |
| Availability: | Ships in 7 to 10 days |
Additional Information: Dnmt3b (Human) antibody
| Antigen | DNA Methyltransferase 3b (Dnmt3b) |
| Immunogen | Synthetic peptide: MKGDSRHLNEEEGA-C, corresponding to amino acids 1-14 ofMouse Dnmt3b. Cellular Location: Nuclear |
| Reactivity | Human, Mouse (Murine) |
| Antibody Type | Polyclonal |
| Format | Aff - Purified |
| Description | DNA methyltransferases methylate the 5-position of cytosine in the context of CpGdinucleotides. DNA methylation is crucial for normal embryonic development, geneticimprinting, and X-chromosome inactivation. Hypermethylation of DNA has also beenimplicated in tumorigenesis through improper methylation of growth regulatory genepromoter regions. Synonyms: ICF antibody, M.HsaIIIB antibody |
| Host | Rabbit |
| Specificity | This antibody detects DNA methyltransferase 3b (Dnmt3b) from human and mousetissues and cells as well as recombinant human Dnmt3b. This antibody detects, to alesser extent, full-length human recombinant Dnmt3a. Cross-reacts with Human and Mouse. Not yet tested in other species. |
Application Details: Dnmt3b (Human) antibody
| Application | ChIP, Western Blotting (WB) |
| Application Notes | Suggested working dilutions *chromatin immunoprecipitation, Western Blot * Investigator should determine optimal working dilutions. This antibody can be used in Chromatin Immunoprecipitation and Western Blot. ByWestern Blot, a 130 kDa band is seen in P19 nuclear extracts. Recommended Starting Dilutions*: ChIP: 2ug/10<,sup>,6<,/sup>, cellsWB: 2.0 ug/ml. Not tested in other applications.*Optimal dilutions should be determined by the end user. * Other applications have not been tested. Positive Control:P19 nuclear extracts. |
| Concentration | 1 mg/ml |
| Buffer | PBS with 1 mg/ml BSA containing 0.05% sodium azide 0.1 mg purified antisera. |
| Storage | Store at -20 degrees C. Avoid Freeze/Thaw Cycles |
| Research Area | DNA/RNA |
| Restrictions | For Research Use only |
External Information: Dnmt3b (Human) antibody
| Google Scholar | Find more references for antigen DNA Methyltransferase 3b (Dnmt3b) on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen DNA Methyltransferase 3b (Dnmt3b) (Bioinformatic Harvester (EMBL)) |
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