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Product details for Dnmt3b-ChIP Grade (Human) antibody
Dnmt3b-ChIP Grade (Human) antibody
Overview
| Antigen: | Dnmt3b-ChIP Grade |
| Antibody Type: | Polyclonal |
| Application: | ChIP assay, Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine) |
| Host: | Rabbit |
| Quantity: | |
| Price: | 527,49 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN147097 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Dnmt3b-ChIP Grade (Human) antibody
| Antigen | Dnmt3b-ChIP Grade |
| Immunogen | Synthetic peptide: MKGDSRHLNEEEGA-C, corresponding to amino acids 1-14 of Mouse Dnmt3b. |
| Reactivity | Human, Mouse (Murine) |
| Antibody Type | Polyclonal |
| Format | Liquid |
| Isotype | IgG »Matching secondary antibodies |
| Description | DNA methyltransferases methylate the 5-position of cytosine in the context of CpG dinucleotides. DNA methylation is crucial for normal embryonic development, genetic imprinting, and X-chromosome inactivation. Hypermethylation of DNA has also been implicated in tumorigenesis through improper methylation of growth regulatory gene promoter regions. |
| Host | Rabbit |
| Specificity | This antibody detects DNA methyltransferase 3b (Dnmt3b) from human and mouse tissues and cells as well as recombinant human Dnmt3b. This antibody detects, to a lesser extent, full-length human recombinant Dnmt3a. |
Application Details: Dnmt3b-ChIP Grade (Human) antibody
| Application | ChIP assay, Western Blotting (WB) |
| Application Notes | ChIP: Use 2ug for 10^6 cells. WB: Use at a concentration of 2.0 ug/ml. Predicted molecular weight: 97.5 kDa. Can be blocked with GTX24922 Dnmt3b peptide Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 1 mg/ml |
| Purity | Immunogen affinity purified |
| Buffer | PBS, 1 mg/ml BSA, 0.05% sodium azide |
| Storage | Store at -20 C or below. |
| Restrictions | For research use only |
External Information: Dnmt3b-ChIP Grade (Human) antibody
| Google Scholar | Find more references for antigen Dnmt3b-ChIP Grade on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Dnmt3b-ChIP Grade (Bioinformatic Harvester (EMBL)) |
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