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Product details for E6AP (Human) antibody
E6AP (Human) antibody
Overview
| Antigen: | UBE3A / E6AP |
| Antibody Type: | Polyclonal |
| Application: | Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Xenopus |
| Host: | Rabbit |
| Quantity: | |
| Price: | 448,63 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN153040 |
| Availability: | Ships in 7 to 10 days |
Additional Information: E6AP (Human) antibody
| Antigen | UBE3A / E6AP |
| Immunogen | A synthetic peptide made to a portion of human ubiquitin protein ligase E3A encodedwithin exon 7 (LocusLink ID 7337). |
| Reactivity | Human, Mouse (Murine), Xenopus |
| Antibody Type | Polyclonal |
| Format | Purified |
| Description | E6AP was originally identified as the ubiquitin-protein ligase involved in humanpapillomavirus E6-mediated p53 degradation. It has since been shown to act as an E3ubiquitin-protein ligase catalyzing the ubiquitination of several other protein substrates. Ubiquitin E3 ligases are overexpressed in many human cancers and their inhibitionleads to growth suppression or apoptosis. |
| Host | Rabbit |
| Specificity | This antibody is specific for E6AP. ABIN153040 recognizes human and mouse. Other species have not been tested. Reactivity with Xenopus laevis UBE3A is likely owing to sequence homology with theimmunogen used for this antibody. |
Application Details: E6AP (Human) antibody
| Application | Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | By Western Blot, this antibody recognizes a band at ~110 kDa, representing E6AP. This antibody may be used for immunoprecipitation, as well.Suggested working dilutions: *Western Blot - 1:1,000-1:10,000Immunoprecipitation - 1-4 ug/mg lysateImmunohistochemistry - ND*The investigator should determine the optimal working dilution for a specific application. |
| Concentration | 1 mg/ml |
| Buffer | 0.1 ml of rabbit antisera (1 mg/ml) with 0.1% sodium azide. |
| Storage | Store at 2-8 degrees Celcius. |
| Restrictions | For Research Use only |
External Information: E6AP (Human) antibody
| Google Scholar | Find more references for antigen UBE3A / E6AP on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen UBE3A / E6AP (Bioinformatic Harvester (EMBL)) |
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