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Product details for ER beta (Rat) antibody
ER beta (Rat) antibody
Overview
| Antigen: | Estrogen Receptor beta |
| Antibody Type: | Polyclonal |
| Application: | Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB) |
| Reactivity: | Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 475,82 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN152870 |
| Availability: | Ships in 7 to 10 days |
Additional Information: ER beta (Rat) antibody
| Antigen | Estrogen Receptor beta |
| Immunogen | Synthetic peptide: CCSTEDSKNKEGSQNLQSQ, corresponding to amino acids 467-485of Mouse Estrogen Receptor (beta). Cellular Location: Nuclear |
| Reactivity | Rat |
| Antibody Type | Polyclonal |
| Format | Aff - Purified |
| Description | "Steroid receptors are ligand-dependent intracellular proteins that stimulate transcriptionof specific genes by binding to specific DNA sequences following activation by theappropriate hormone. Estrogen receptor (ER) was first cloned in 1987 and has beenshown to be expressed and transcriptionally active in a number of tissues includingovary, testis, prostate and brain. Until recently, only the ""classical"" ER (ERalpha) has been known. However, a new estrogen binding receptor, referred to as ERbeta, has recently been cloned in rat and humans.ER beta has been shown to be a high affinity estrogen binding protein capable ofinitiating transcription of genes under the control of estrogen response elements (ERE Synonyms: ER beta" |
| Host | Rabbit |
| Specificity | Cross-reacts with Rat. Expected to cross-react with Mouse (94% identity withimmunogen) due to sequence homology. Not yet tested in other species. |
Application Details: ER beta (Rat) antibody
| Application | Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB) |
| Application Notes | Suggested working dilutions *immunohistochemistry, Western Blot * Investigator should determine optimal working dilutions. This antibody can be used for Immunohistochemistry and Western Blot. By WesternBlot a 55kDa band is seen in rat brain homogenate (predicted MW 59 kDa). Recommended Starting Concentrations*: IHC: 1-2 ug/ml WB: 2ug/10<,sup>,6 cells lar weight: *Optimal dilutions should be determined by the end user. * Other applications have not been tested. Positive Control:HEK cell extract. |
| Concentration | 1 mg/ml |
| Buffer | PBS with 1mg/ml BSA containing 0.05% sodium azide 0.05 mg purified antisera. Preservative: Contains sodium azide |
| Storage | Store at -20 degrees Celcius. |
| Restrictions | For Research Use only |
External Information: ER beta (Rat) antibody
| Google Scholar | Find more references for antigen Estrogen Receptor beta on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Estrogen Receptor beta (Bioinformatic Harvester (EMBL)) |
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