Endothelin-1 Fab'-HRP antibody

Overview

Antigen	Endothelin-1 Fab'-HRP
Immunogen	Synthetic peptide of a part of ET-1 (Common parts with Human, Bovine, Canine, Mouse, Porcine, and Rat) IgG
Antibody Type	Polyclonal
Isotype	IgG »Matching secondary antibodies
Description	Endothelins are 21 amino acid peptides that are produced ubiquitously by vascular endothelial cells, smooth muscle cells, and other cells in different organs. Endothelins are secreted as big-endothelins that are converted to active proteins by the endothelin-converting enzyme. These peptides possess many biological activities, such as vasoconstriction and mitogenesis, and are involved in numerous physiological and pathophysiological processes in humans. Elevated plasma levels of endothelin have been associated with heart failure, and increased immunoreactivity for endothelin is observed in transplant coronary artery disease. Endothelin-1 (ET-1) is known as the most potent vasoconstrictor substance.
Host	Rabbit
Specificity	Endothelin-1 100.0 % Endothelin-2 277.0 % Endothelin-3 0.1 % Big Endothelin-1 80.3 % Big Endothelin-2 277.0 % Big Endothelin-3 0.1 % VIC 0.1 %

Application	ELISA
Application Notes	This antibody can be applied for ELISA method in concentration with 3ug/ml.
Purification	Protein A
Buffer	Lyophilized product from 1% BSA in PB : IgG Fab' Conjugated: Horseradish Peroxidase (HRP) Enzyme Purification: Purified by protein A
Storage	Lyophilized product, 5 years at 2-8:solution, 2 years at -20
Restrictions	For Research Use only

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