购物车
帮助
抗原
产品详细信息： FADD (Human) antibody
FADD (Human) antibody
概述
| 抗原: | FADD |
| 抗体类型: | 单克隆抗体 |
| 应用范围: | Dot Blot (Dot), ELISA, Immunoprecipitation (IP) |
| 目标物种: | Human |
| 抗体来源: | Mouse |
| 规格: | |
| 价格: | 2.670,62 ¥ (加上运费和增值税, Invoice in EUR) |
| 货号: | ABIN144030 |
| 发货时间: | 7 to 10 days until shipment |
详细信息: FADD (Human) antibody
| 抗原 | FADD |
| 免疫原 | Recombinant full length protein (Human). |
| 目标物种 | Human |
| 抗体类型 | 单克隆抗体 |
| 状态 | Liquid |
| 抗体同种型 | IgG1 »相配的二抗 |
| 描述 | FADD (Fas Associated Death Domain) is an apoptosis adapter molecule enabling transduction of the apoptosis signal initiated via the FasL/Fas receptor interaction. The protein contains a C-terminal death domain that interacts with the Fas receptor death domain. The N-terminus contains a death effectors domain (DED, which recruits caspase to the death inducing signaling complex (DISC) and initiates the apoptotic caspase cascade. FADD is implicated in non-apoptotic cellular pathways such as the regulation of cell cycle machinery in T lymphocytes. This is connected to the phosphorylation state of FADD and to the FasL/TRAIL-induced transcriptional activation of c-fos protooncogene. FADD also interacts with the hepatitis C virus core protein in the HEK-293 cell line. |
| 克隆 | FD19 |
| 抗体来源 | Mouse |
使用细节: FADD (Human) antibody
| 应用范围 | Dot Blot (Dot), ELISA, Immunoprecipitation (IP) |
| 应用备注 | Dot: Use at a concentration of 0.5-1 ug/ml, determined using total cell extracts of A431 cells. ELISA: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| 浓度 | 2 mg/ml |
| 纯度 | Immunogen affinity purified |
| 缓冲液 | Preservative: 15mM Sodium AzideConstituents: 0.01M PBS. pH 7.4 |
| 限制 | For research use only |
