Product details for  H-2Dk Mouse (Murine) antibody
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H-2Dk Mouse (Murine) antibody

Overview

Image for H-2Dk Mouse (Murine) antibody
Antigen: H-2Dk
Antibody Type: Monoclonal
Application: Flow Cytometry (FACS)
Reactivity: Mouse (Murine)
Host: Mouse
Quantity: 50 µg (Product variants)
Price: 76,00 €   (Plus shipping costs and VAT)
Order number: ABIN156516
Availability: Ships within 7 to 10 days
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Additional Information:  H-2Dk Mouse (Murine) antibody

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Antigen H-2Dk
Immunogen C3H mouse splenocytes
Reactivity Mouse (Murine)
Antibody Type Monoclonal
Format Purified
Isotype Mouse IgG2a, kappa Mouse (C3H.SW) IgG2a, kappa »Matching secondary antibodies
Description The 15-5-5 antibody reacts with the H-2D MHC class I alloantigen expressed on nucleated cells from mice of the H-2D haplotype. H-2D is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins. The 15-5-5 antibody weakly cross-reacts with H-2K and with cells from mice of the H-2 haplotype. Reactivity with other haplotypes (e.g., a,b,p,q,r,s) has not been reported. Distribution: Nucleated cells of the H-2D haplotype Function: Antigen presentation Synonyms: MHC class I Structure: MHC class I
Clone 15-05-2005
Host Mouse

Application Details:  H-2Dk Mouse (Murine) antibody

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Application Flow Cytometry (FACS)
Application Notes Additional reported applications (for the relevant formats) include: complement-mediated cytotoxicity. Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is < 1.0 µg per 10 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Purification The antibody was purified by affinity chromatography.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Storage The antibody solution should be stored undiluted at 4°C.
Restrictions For Research Use only

Publications:  H-2Dk Mouse (Murine) antibody

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Publications Pamer, Cresswell:
"Mechanisms of MHC class I--restricted antigen processing."
In: Annual review of immunology , Vol. 16, pp. 323-58, 1998/01 (PubMed)

Watts:
"Capture and processing of exogenous antigens for presentation on MHC molecules."
In: Annual review of immunology , Vol. 15, pp. 821-50, 1997/01 (PubMed)

York, Rock:
"Antigen processing and presentation by the class I major histocompatibility complex."
In: Annual review of immunology , Vol. 14, pp. 369-96, 1996/01 (PubMed)

Ozato, Mayer, Sachs:
"Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens."
In: Journal of immunology (Baltimore, Md. : 1950) , Vol. 124, Issue 2, pp. 533-40, 1980/01 (PubMed)

Yamamoto, Fujihashi, Kawabata et al.:
"A mucosal intranet: intestinal epithelial cells down-regulate intraepithelial, but not peripheral, T lymphocytes."
In: Journal of immunology (Baltimore, Md. : 1950) , Vol. 160, Issue 5, pp. 2188-96, 1998/01 (PubMed)

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C3H/He mouse splenocytes stained with 15-5-5 FITC

Image for H-2Dk Mouse (Murine) antibody (1)

External Information:  H-2Dk Mouse (Murine) antibody

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Google Scholar Find more references for clone 15-05-2005 on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen H-2Dk (Bioinformatic Harvester (EMBL))