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Product details for H-2Kb/H-2Dd Mouse (Murine) antibody
H-2Kb/H-2Dd Mouse (Murine) antibody
Overview
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| Antigen: | H-2Kb/H-2Dd |
| Antibody Type: | Monoclonal |
| Application: | Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)) |
| Reactivity: | Mouse (Murine) |
| Host: | Mouse |
| Quantity: | |
| Price: | 70,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN156671 |
| Availability: | Ships within 7 to 10 days |
Additional Information: H-2Kb/H-2Dd Mouse (Murine) antibody
| Antigen | H-2Kb/H-2Dd |
| Immunogen | BDF Splenocytes |
| Reactivity | Mouse (Murine) |
| Antibody Type | Monoclonal |
| Format | Purified |
| Isotype | Mouse IgG2a, kappa Mouse (C3H) IgG2a, kappa »Matching secondary antibodies |
| Description | The 34-1-2S antibody reacts with the H-2K/H-2D MHC class I alloantigens expressed on nucleated cells from mice of the H-2K/H-2D haplotype. H-2K/H-2D is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins. The 34-1-2S antibody cross-reacts with H-2K MHC class I alloantigens of the b, s, r, q, or p haplotypes. Distribution: Nucleated cells of the H-2K/H-2D haplotype Function: Antigen presentation Synonyms: MHC class I Structure: MHC class I |
| Clone | 34-1-2S |
| Host | Mouse |
| Specificity | Cross-reacts with h-2 mhc class i alloantigens of the b |
Application Details: H-2Kb/H-2Dd Mouse (Murine) antibody
| Application | Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)) |
| Application Notes | Additional reported applications (for the relevant formats) include: immunoprecipitation, complement-mediated cytotoxicity, and immunohistochemistry of acetone-fixed frozen sections. Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is < 0.5 µg per 10 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Purification | The antibody was purified by affinity chromatography. |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Storage | The antibody solution should be stored undiluted at 4°C. |
| Restrictions | For Research Use only |
Publications: H-2Kb/H-2Dd Mouse (Murine) antibody
| Publications |
Pamer, Cresswell: "Mechanisms of MHC class I--restricted antigen processing." In: Annual review of immunology , Vol. 16, pp. 323-58, 1998/01 (PubMed) Watts: "Capture and processing of exogenous antigens for presentation on MHC molecules." In: Annual review of immunology , Vol. 15, pp. 821-50, 1997/01 (PubMed) York, Rock: "Antigen processing and presentation by the class I major histocompatibility complex." In: Annual review of immunology , Vol. 14, pp. 369-96, 1996/01 (PubMed) Ozato, Mayer, Sachs: "Monoclonal antibodies to mouse major histocompatibility complex antigens." In: Transplantation , Vol. 34, Issue 3, pp. 113-20, 1982/01 (PubMed) |
Images: H-2Kb/H-2Dd Mouse (Murine) antibody
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C57BL/6 mouse splenocytes stained with 34-1-2S PE C3H/He mouse splenocytes stained with 34-1-2S PE
C3H/He mouse splenocytes stained with 34-1-2S PE |
Product variants
External Information: H-2Kb/H-2Dd Mouse (Murine) antibody
| Google Scholar | Find more references for clone 34-1-2S on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen H-2Kb/H-2Dd (Bioinformatic Harvester (EMBL)) |
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