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Product details for HP1 beta (Human) antibody
HP1 beta (Human) antibody
Overview
| Antigen: | HP1 beta |
| Antibody Type: | Monoclonal |
| Application: | ELISA, Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine) |
| Host: | Rat |
| Quantity: | |
| Price: | 390,43 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN144330 |
| Availability: | 7 to 10 days until shipment |
Additional Information: HP1 beta (Human) antibody
| Antigen | HP1 beta |
| Immunogen | 71 amino acid fusion protein corresponding to the c-terminal region of M31 (human/mouse). |
| Reactivity | Human, Mouse (Murine) |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG2b »Matching secondary antibodies |
| Description | Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing. Component of heterochromatin. Recognizes and binds histone H3, leading to epigenetic repression. May interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. |
| Clone | MAC353 |
| Host | Rat |
| Specificity | ABIN144330 recognises the M31 molecule in mouse and the homologous HP1 HS beta molecule in man. |
Application Details: HP1 beta (Human) antibody
| Application | ELISA, Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Western Blotting (WB) |
| Application Notes | ELISA: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 26 kDa (predicted molecular weight: 22.2 kDa). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Purity | Tissue culture supernatant |
| Buffer | Preservative: 0.09% Sodium Azide |
| Storage | Store at 4 C. Aliquot and store at -20 C long-term. |
| Restrictions | For research use only |
External Information: HP1 beta (Human) antibody
| Google Scholar | Find more references for clone MAC353 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen HP1 beta (Bioinformatic Harvester (EMBL)) |
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