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抗原
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Hematopoiesis related Macrophage
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免疫原
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Adherent bone marrow cells.
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目标物种
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Mouse (Murine)
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抗体类型
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单克隆抗体
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状态
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Liquid
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抗体同种型
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IgG2c »相配的二抗
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描述
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Macrophage are any of the many forms of mononuclear phagocytes found in tissues. Mononuclear phagocytes arise from hematopoietic stem cells in the bone marrow. After passing through the monoblast and promonocyte states of the monocyte stage, they enter the blood, circulating for about 40 hours. They then enter tissues and increase in size, phagocytic activity, and lysosomal enzyme content and become macrophages. The morphology of macrophages varies among different tissues and between normal and pathologic states, and not all macrophages can be identified by morphology alone. However, most macrophages are large cells with a round or indented nucleus, a well developed Golgi apparatus, abundant endocytotic vacuoles, lysosomes, and phagolysosomes, and a plasma membrane covered with ruffles or microvilli. Among the functions of macrophages are nonspecific phagocytosis and pinocytosis, specific phagocytosis of opsonized microorganisms mediated by Fc receptors and complement receptors, kil
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克隆
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ER-HR3
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抗体来源
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Rat
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特异性
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Ab15636 recognises the majority of blood monocytes and a subset of mature resident macrophages, especially those located in hemopoietic organs. Does not cross react with other leukocytes.The antigen is found on up to 70% of circulating monocytes, all othe
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