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Product details for Hepatitis B x Protein antibody
Hepatitis B x Protein antibody
Overview
| Antigen: | Hepatitis B Virus Protein X (HBx) |
| Antibody Type: | Monoclonal |
| Application: | Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB) |
| Host: | Mouse |
| Quantity: | |
| Price: | 330,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN120930 |
| Availability: | Ships in 3 to 10 days |
Additional Information: Hepatitis B x Protein antibody
| Antigen | Hepatitis B Virus Protein X (HBx) |
| Immunogen | Baculovirus expressed recombinant HBx. |
| Antibody Type | Monoclonal |
| Format | Purified |
| Isotype | IgG1 »Matching secondary antibodies |
| Clone | X36C |
| Host | Mouse |
| Specificity | Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein-protein interaction. ABIN120930 detects hepatitis B x (HBx) protein from transfected human cells. |
Application Details: Hepatitis B x Protein antibody
| Application | Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | ELISA. Immunoprecipitation (This antibody is not capable of immunoprecipitating HBx complexed with HBx interacting protein XIP). Western Blot (1 ug/ml, detects a single ~17 kDa protein representing HBx). Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user. |
| Concentration | 1 mg/ml |
| Buffer | This antibody is supplied as liquid, purified immunoglobulin fraction in PBS buffer with 0.05% sodium azide as preservative. |
| Storage | Store the antibody at –20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Research Area | Virology |
| Restrictions | Research only |
External Information: Hepatitis B x Protein antibody
| Google Scholar | Find more references for clone X36C on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Hepatitis B Virus Protein X (HBx) (Bioinformatic Harvester (EMBL)) |
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