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Antigen
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Hsp70
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Immunogen
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Human recombinant Hsp 70 over expressed in E. coli.
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Reactivity
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Human
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Antibody Type
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Monoclonal
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Format
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Liquid
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Isotype
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IgG2b »Matching secondary antibodies
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Description
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The Hsp 70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined. The human Hsp 70 family members include: Hsp 70, a protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells, Hsp 72, a 72 kDa protein that is induced exclusively under stress conditions, Hsc 70, or cognate protein, is a 72 kDa, constitutively expressed, protein which is involved in the uncoating of clathrin coated vesicles, GRP78, or BiP, is a glucose regulated 78 kDa protein localized in the endoplasmic reticulum, and p75, or Hsp 75, a 75 kDa protein that is found within the mitochondria.
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Clone
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4G4
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Host
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Mouse
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Specificity
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ABIN146128 detects heat shock protein 70 kDa (Hsp 70) from human tissues. This antibody specifically detects Hsp 70 and does not cross-react with other members of the Hsp 70 family.
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