Product details for I-A antibody
I-A antibody
Overview
| Antigen: | I-A |
| Antibody Type: | Monoclonal |
| Application: | Flow Cytometry (FACS), Immunohistochemistry (IHC) |
| Host: | Mouse |
| Quantity: | |
| Price: | 237,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN139968 |
| Availability: | 7 to 10 days until shipment |
Additional Information: I-A antibody
| Antigen | I-A |
| Immunogen | Rat thymocyte membrane glycoproteins |
| Antibody Type | Monoclonal |
| Format | Lyophilized |
| Isotype | IgG1 (Mouse) »Matching secondary antibodies |
| Description | Recognises a polymorphic determinant of rat Ia antigen (RT1.Bu) present on Lewis, Wistar and AO strain rats but not BN, DA or PVG/c strains (1,2). The antibody cross reacts with mouse strains (MHC haplotypes b and s) and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region. It recognises Ia antigens on B-cells, dendritic cells and certain epithelial cells (1,3,4). It is particularly useful for distinguishing Ia positive cells from different rat strains, eg for recognising cells of donor origin in bone marrow reconstituted radiation chimeras (3,4). |
| Clone | MRC OX3 |
| Host | Mouse |
| Specificity | Rat 1a antigen |
Application Details: I-A antibody
| Application | Flow Cytometry (FACS), Immunohistochemistry (IHC) |
| Application Notes | Flow cytometry, immunohistology, Flow Cytometry:Use 10ul of the suggested working dilution to label 106 cells in 100ul. |
| Concentration | 1 mg/ml |
| Purity | Purified IgG |
| Buffer | Phosphate buffered saline pH7.4 |
| Storage | Store at +4 C or at -20 C if preferred. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Restrictions | For research use only |
External Information: I-A antibody
| Google Scholar | Find more references for clone MRC OX3 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen I-A (Bioinformatic Harvester (EMBL)) |







