Produktdetails für ICAD (N-term) (Mouse (Murine)) antibody
ICAD (N-term) (Mouse (Murine)) antibody
Übersicht
| Antigen: | ICAD/DFF45 (N-term) |
| Antikörper-Typ: | Polyklonal |
| Applikation: | Western Blotting (WB) |
| Reaktivität: | Mouse (Murine) |
| Wirt: | Rabbit |
| Menge: | |
| Preis: | 320,00 € (Zzgl. Versandkosten und MWSt) |
| Bestellnummer: | ABIN121557 |
| Verfügbarkeit: | Ships in 3 to 10 days |
Produktbeschreibung: ICAD (N-term) (Mouse (Murine)) antibody
| Antigen | ICAD/DFF45 (N-term) |
| Immunogen | Synthetic peptide corresponding to amino acids 312-331 of mouse ICAD. |
| Reaktivität | Mouse (Murine) |
| Antikörper-Typ | Polyklonal |
| Format | Purified |
| Wirt | Rabbit |
| Spezifität | ICAD (Inhibitor of Caspase-Activated DNase) is the murine homologue of human DFF-45. ICAD is cleaved by Caspase-3, releasing CAD which eventually causes degradation of DNA in the nucleus. This antibody recognises a 45kD band in Western blots. |
Anwendungen: ICAD (N-term) (Mouse (Murine)) antibody
| Applikation | Western Blotting (WB) |
| Applikationshinweise | Western blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user. |
| Konzentration | 0.5 mg/ml |
| Buffer | This antibody is supplied as liquid, affinity purified immunoglobulin fraction in PBS with 0.02% sodium azide as preservative. |
| Lagerung | Store the antibody at 4-8°C for one month or at –20°C for longer. This product should be stored undiluted. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Forschungsgebiet | Apoptosis/Necrosis |
| Beschränkungen | Research only |
Publikationen: ICAD (N-term) (Mouse (Murine)) antibody
| Publikationen |
Enari, Sakahira, Yokoyama et al.: "A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD." In: Nature , Vol. 391, Issue 6662, pp. 43-50, 1998/01 (PubMed) Wyllie: "Apoptosis. An endonuclease at last." In: Nature , Vol. 391, Issue 6662, pp. 20-1, 1998/01 (PubMed) |
Weitere Informationen: ICAD (N-term) (Mouse (Murine)) antibody
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