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Détail du produit pour IKK gamma (Human) antibody
IKK gamma (Human) antibody
Aperçu
| Antigène: | I Kappa K gamma (IkKg) (C-term) |
| Type anticorps: | Polyclonal |
| Application: | Western Blotting (WB) |
| Reactivité: | Human |
| Hôte: | Rabbit |
| Quantité: | |
| Prix: | 310,00 € (Plus frais de livraison et TVA) |
| Numéro de commande: | ABIN153159 |
| Disponibilité: | Ships in 7 to 10 days |
Description du produit: IKK gamma (Human) antibody
| Antigène | I Kappa K gamma (IkKg) (C-term) |
| Immunogène | C-terminus of the IKK-gamma protein (proprietary) |
| Reactivité | Human |
| Type anticorps | Polyclonal |
| Format | Aff - Purified |
| Description | Pro-inflammatory cytokines activate the transcription factor NF-kappa B by stimulatingthe activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF-kappa B,at sites that trigger its ubiquitination and degradation. A large, cytokine-responsiveIkappa B kinase (IKK) complex has been purified and the genes encoding 2 of itssubunits have been cloned. These subunits, IKK-alpha and Ikk-beta, are proteinkinases whose function is needed for NF-kappa B activation by pro-inflammatory stimuli. IKK is composed of similar amounts of IKK-alpha, Ikk-beta, which are differentiallyprocessed forms of a third subunit, IKK-gamma. Ikk-gamma interacts preferentially withIKK-beta and is required for the activation of the IKK complex. |
| Hôte | Rabbit |
| Specificité | Reacts with residues 385-399 [RRSPPEEPPDFCCPK] of the IKK-g protein. Recognizes both human isoforms. Human. Other species have not been tested. |
Applications: IKK gamma (Human) antibody
| Application | Western Blotting (WB) |
| Indications d'application | Western blot – Use at 1:500 to 1:1,000 dilution. However, the investigator shoulddetermine the optimal dilution for a specificapplication such as immunohistochemistry. |
| Concentration | 1 mg/ml |
| Buffer | 100 ug in 100 ul (1 mg/ml) in PBS containing 0.02% sodium azide. PBS with 0.02% sodium azide |
| Stock | Store at +2-8°C for 3 months or -20°C for longer periods. Avoid repeated freeze-thawcycles. |
| Restrictions | For Research Use only |
Informations supplémentaires: IKK gamma (Human) antibody
| Google Scholar | Trouver des références supplémentaires pour antigène I Kappa K gamma (IkKg) (C-term) sur Google Scholar™ |
| EMBL Harvester | Recherche humain, souris ou rat génome pour antigène I Kappa K gamma (IkKg) (C-term) (Bioinformatic Harvester (EMBL)) |
