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Product details for JAK3 antibody
JAK3 antibody
Overview
| Antigen: | JAK3 |
| Antibody Type: | Monoclonal |
| Application: | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Host: | Mouse |
| Quantity: | |
| Price: | 553,71 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN103337 |
| Availability: | 7 days until shipment |
Additional Information: JAK3 antibody
| Antigen | JAK3 |
| Immunogen | BALB/C mice were immunized with recombinant protein encoding C-terminus corresponding to amino acid 1076 |
| Antibody Type | Monoclonal |
| Format | Purified Ascites |
| Isotype | IgG2a Kappa »Matching secondary antibodies |
| Clone | A1-14-16 |
| Host | Mouse |
| Specificity | This antibody with a protein of 115 kD. JAK3 is a member of the Janus family of protein tyrosine kinases along with JAK1, JAK2 and Tyk2. JAK3 is activated in response to IL-3 and IL-4 in T cells and myeloid cells. JAK3 activation requires the serine-rich membrane-proximal region of the IL-2 receptor beta-chain. Expression of JAK3 is restricted to NK and T cells. This antibody cross reacts with mouse. |
Application Details: JAK3 antibody
| Application | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Application Notes | Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Colon carcinoma. Cellular localization: Cell membrane, cytoplasmic |
| Buffer | This antibody is supplied as purified ascites containing sodium azide as preservative. |
| Storage | Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label. |
| Research Area | Signaling, Cytokines, Receptors, Kinases/Phosphatases |
| Restrictions | For Research Use only |
External Information: JAK3 antibody
| Google Scholar | Find more references for clone A1-14-16 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen JAK3 (Bioinformatic Harvester (EMBL)) |
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