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Product details for Macrophage Inflammatory Protein 1 alpha (Human) antibody
Macrophage Inflammatory Protein 1 alpha (Human) antibody
Overview
| Antigen: | Macrophage Inflammatory Protein 1 alpha |
| Antibody Type: | Polyclonal |
| Reactivity: | Human |
| Quantity: | |
| Price: | 247,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN148841 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Macrophage Inflammatory Protein 1 alpha (Human) antibody
| Antigen | Macrophage Inflammatory Protein 1 alpha |
| Reactivity | Human |
| Antibody Type | Polyclonal |
| Description | MIP1 alpha and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated. |
Application Details: Macrophage Inflammatory Protein 1 alpha (Human) antibody
| Application Notes | For ELISA: Use at a dilution of 1:1000-1:2000. ELISA will detect human MIP-1a from supernatants or lysates of 2 x 10^6 endotoxin-stimulated human peripheral blood mononuclear cells (PBMC). PBMC are stimulated for 24 hours with 1% (v/v) human serum plus 10 ng/mL E. Coli LPS. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher |
| Concentration | Whole antiserum |
| Purity | Unpurified |
| Buffer | Whole antiserum containing 0.01% Sodium Azide |
| Restrictions | For research use only |
External Information: Macrophage Inflammatory Protein 1 alpha (Human) antibody
| Google Scholar | Find more references for antigen Macrophage Inflammatory Protein 1 alpha on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Macrophage Inflammatory Protein 1 alpha (Bioinformatic Harvester (EMBL)) |
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