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Muscarinic 1 Acetylcholine Receptor (Mouse (Murine)) antibody

Overview


	Antigen:	Muscarinic M1 Acetylcholine Receptor
	Antibody Type:	Polyclonal
	Application:	Western Blotting (WB)
	Reactivity:	Human, Mouse (Murine)
	Host:	Rabbit
	Quantity:	0.2 mg (1.0 mg/ml)
	Price:	330,00 € (Plus shipping costs and VAT)
	Order number:	ABIN122728
	Availability:	Ships in 3 to 10 days

Antigen	Muscarinic M1 Acetylcholine Receptor
Immunogen	Fusion protein containing amino acids 269-320 from human m1 AChR. This sequence is completely conserved in mrat, and bovine protein. ouse,
Reactivity	Human, Mouse (Murine)
Antibody Type	Polyclonal
Format	Aff - Purified
Host	Rabbit
Specificity	Acetylcholine receptors (AChRs) mediate synaptic transmission at the neuromuscular junction. The channel-linked AChR that mediates rapid, excitatory actions of acetylcholine is called nicotinic AChR (nAChR) because it can be activated by nicotine. The non-channel linked AChR that medicates the slow actions of acetylcholine, which can be either inhibitory or excitatory, is called muscarinic AChR (mAChR) because it can be activated by muscarine. The mAChRs are present in neurons of the central and peripheral nervous systems, cardiac and smooth muscle and various exocrine glands. There are 5 subtypes (m1-m5) of the receptor that have a tissue specific pattern of expression. The m1 receptor is localized primarily in brain tissue. ABIN122728 detects recombinant mouse muscarinic acetylcholine receptor 1 (m1AChR).

Application	Western Blotting (WB)
Application Notes	Western Blot (2ug/ml, detects an ~64 kDa protein representing recombinant mouse m1AChR). This antibody is not recommended for immunohisto-chemistry procedures. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration	1.0 mg/ml
Buffer	This antibody is supplied as liquid, epitope affinity purified immunoglobulin fraction in PBS with 0.05% sodium azide as preservative and 1 mg/ml BSA as stabilizer.
Storage	Store the antibody at –20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area	Neurotransmitters, Hormones, Receptors
Restrictions	Research only

Figure 1 shows a Western blot on recombinant m1AChR using ABIN122728.

Image for Muscarinic 1 Acetylcholine Receptor (Mouse (Murine)) antibody (1)

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