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Product details for Muscarinic M1 (Mouse (Murine)) antibody
Muscarinic M1 (Mouse (Murine)) antibody
Overview
| Antigen: | Muscarinic M1 Acetylcholine Receptor |
| Antibody Type: | Polyclonal |
| Application: | Western Blotting (WB) |
| Reactivity: | Bovine, Human, Mouse (Murine), Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 350,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN152781 |
| Availability: | Ships in 7 to 10 days |
Additional Information: Muscarinic M1 (Mouse (Murine)) antibody
| Antigen | Muscarinic M1 Acetylcholine Receptor |
| Immunogen | Fusion protein containing amino acids 269-320 from human m1 AChR. This sequence iscompletely conserved in mouse, rat, and bovine protein. |
| Reactivity | Bovine, Human, Mouse (Murine), Rat |
| Antibody Type | Polyclonal |
| Format | Aff - Purified |
| Description | Acetylcholine receptors (AChRs) mediate synaptic transmission at the neuromuscularjunction. The channel-linked AChR that mediates rapid, excitatory actions ofacetylcholine is called nicotinic AChR (nAChR) because it can be activated by nicotine.The non-channel linked AChR that medicates the slow actions of acetylcholine, whichcan be either inhibitory or excitatory, is called muscarinic AChR (mAChR) because itcan be activated by muscarine. The mAChRs are present in neurons of the central andperipheral nervous systems, cardiac and smooth muscle and various exocrine glands.There are 5 subtypes (m1-m5) of the receptor that have a tissue specific pattern ofexpression. The m1 receptor is localized primarily in brain tissue. |
| Host | Rabbit |
| Specificity | Detects recombinant mouse Muscarinic Acetylcholine Receptor 1 (m1AChR). Cross-reacts with Mouse.Expected to cross-react with Human and Rat due to sequencehomology.Not yet tested in other species. |
Application Details: Muscarinic M1 (Mouse (Murine)) antibody
| Application | Western Blotting (WB) |
| Application Notes | Suggested working dilutions *Western Blot * Investigator should determine optimal working dilutions. Western Blot: use at a concentration of 2 ug/ml.Not tested in other applications.Optimaldilutions / concentrations should be determined by the end user.By Western blot, thisantibody detects an ~64 kDa protein representing recombinant mouse m1AChR. Thisantibody is not recommended for immunohistochemical procedures. * Other applications have not been tested. |
| Buffer | PBS, 1 mg/ml BSA, 0.05% sodium azide 200 micrograms Liquid. |
| Storage | Aliquot and store at -20 degrees C. Avoid repeated freeze / thaw cycles. |
| Research Area | Neurotransmitters, Hormones, Receptors |
| Restrictions | For Research Use only |
External Information: Muscarinic M1 (Mouse (Murine)) antibody
| Google Scholar | Find more references for antigen Muscarinic M1 Acetylcholine Receptor on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Muscarinic M1 Acetylcholine Receptor (Bioinformatic Harvester (EMBL)) |
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