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产品详细信息： NACHT, leucine rich repeat and PYD containing 12 (NALP12)...
NACHT, leucine rich repeat and PYD containing 12 (NALP12) (Human) antibody
概述
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| 抗原: | NACHT, leucine rich repeat and PYD containing 12 (NALP12) |
| 抗体类型: | 单克隆抗体 |
| 应用范围: | ELISA, Western Blotting (WB) |
| 目标物种: | Human |
| 抗体来源: | Mouse |
| 规格: | |
| 价格: | 396,00 € (加上增值税, €10.00干冰费用和增值税) |
| 货号: | ABIN169494 |
| 发货时间: | Delivery in 7 to 10 days |
详细信息: NACHT, leucine rich repeat and PYD containing 12 (NALP12) (Human) antibody
| 抗原 | NACHT, leucine rich repeat and PYD containing 12 (NALP12) |
| 基因ID | 91662 |
| 免疫原 | NALP12 (AAH28069, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: (without GST) MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLE MAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQS |
| 目标物种 | Human |
| 抗体类型 | 单克隆抗体 |
| 抗体同种型 | IgG2a Kappa »相配的二抗 |
| 描述 | NACHT, leucine rich repeat and PYD containing 12 NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003). Mouse monoclonal antibody raised against a partial recombinant NALP12. Synonyms: PYPAF7, RNO2 |
| 克隆 | 3B5 |
| 抗体来源 | Mouse |
使用细节: NACHT, leucine rich repeat and PYD containing 12 (NALP12) (Human) antibody
| 应用范围 | ELISA, Western Blotting (WB) |
| 应用备注 | Quality Control: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. |
| 缓冲液 | In 1x PBS, pH 7.2 Western Blot detection against Immunogen (35.10 KDa) . |
| 贮藏 | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| 限制 | For Research Use only |
图像: NACHT, leucine rich repeat and PYD containing 12 (NALP12) (Human) antibody
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Western Blot detection against Immunogen (35.10 KDa) .
The detection limit for recombinant GST tagged NALP12 is approximately 0.3ng/ml as a capture antibody. |
