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Produktdetails für NACHT, leucine rich repeat and PYD containing 12 (NALP12)...
NACHT, leucine rich repeat and PYD containing 12 (NALP12) (Human) antibody
Übersicht
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| Antigen: | NACHT, leucine rich repeat and PYD containing 12 (NALP12) |
| Antikörper-Typ: | Monoklonal |
| Applikation: | ELISA, Western Blotting (WB) |
| Reaktivität: | Human |
| Wirt: | Mouse |
| Menge: | |
| Preis: | 396,00 € (Zzgl. Versandkosten , €10.00 Trockeneispauschale sowie MWSt) |
| Bestellnummer: | ABIN169494 |
| Verfügbarkeit: | Delivery in 7 to 10 days |
Produktbeschreibung: NACHT, leucine rich repeat and PYD containing 12 (NALP12) (Human) antibody
| Antigen | NACHT, leucine rich repeat and PYD containing 12 (NALP12) |
| Gen-ID | 91662 |
| Immunogen | NALP12 (AAH28069, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: (without GST) MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLE MAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQS |
| Reaktivität | Human |
| Antikörper-Typ | Monoklonal |
| Isotyp | IgG2a Kappa »Passende Sekundärantikörper |
| Beschreibung | NACHT, leucine rich repeat and PYD containing 12 NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003). Mouse monoclonal antibody raised against a partial recombinant NALP12. Synonyms: PYPAF7, RNO2 |
| Klon | 3B5 |
| Wirt | Mouse |
Anwendungen: NACHT, leucine rich repeat and PYD containing 12 (NALP12) (Human) antibody
| Applikation | ELISA, Western Blotting (WB) |
| Applikationshinweise | Quality Control: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. |
| Buffer | In 1x PBS, pH 7.2 Western Blot detection against Immunogen (35.10 KDa) . |
| Lagerung | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Beschränkungen | For Research Use only |
Bilder: NACHT, leucine rich repeat and PYD containing 12 (NALP12) (Human) antibody
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Western Blot detection against Immunogen (35.10 KDa) .
The detection limit for recombinant GST tagged NALP12 is approximately 0.3ng/ml as a capture antibody. |
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