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Product details for NBS1 (Human) antibody
NBS1 (Human) antibody
Overview
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| Antigen: | NBS1 |
| Antibody Type: | Monoclonal |
| Application: | Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 271,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN136268 |
| Availability: | 7 to 10 days until shipment |
Additional Information: NBS1 (Human) antibody
| Antigen | NBS1 |
| Immunogen | The complete coding region of the human p95/NBS1 expressed in E. coli. |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | Nijmegen breakage syndrome (NBS, nibrin) is an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The 1C3 antibody recognizes the 95 kDa NBS protein which contains a fork FHA head-associated domain that is adjacent to BRCT, a breast cancer C terminal domain, that has been implicated in protein-protein interactions. NBS is member of the Mre11/Rad50, p400 double-strand break repair complex involved in double-strand break repair and cell-cycle checkpoint functions. |
| Clone | 1C3 |
| Host | Mouse |
Application Details: NBS1 (Human) antibody
| Application | Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | Extensive washing may be necessary. This product does not require protein digestion or microwave antigen retrieval prior to staining. |
| Concentration | 1 mg/ml |
| Purity | Protein G Affinity Purified |
| Buffer | PBS, pH 7.4. No preservatives. |
| Storage | Store at -80 C. Avoid repeat freeze-thaw cycles. |
| Restrictions | For research use only |
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