抗原	N-Cadherin(760)
免疫原	Synthetic peptide of aa 746-761 (KRRDKERQAKQLLI) of human N-Cadherin Purification: Affinity purified with synthetic peptide
目标物种	Human
抗体类型	多克隆抗体
抗体同种型	IgG »相配的二抗
描述	Cadherins are a family of Ca2+-dependent intercellular adhesion molecules. They play an important role in cell-cell interaction, histogenesis and cellular transformation, and association with the actin cytoskeleton regulates their function by a complex of cytoplasmic proteins called the catenins (, , ). Among the cadherin protein family, N-cadherin function is indirectly regulated by endogenous kinases and phosphatases. Tyrosine phosphorylation of -catenin complexed with N-cadherin results in dissociation of N-cadherin from actin. However, Thus, N-cadherin is an integral adhesion molecule whose function is regulated by protein-protein interactions and phosphorylation/dephosphory- lation events.
抗体来源	Rabbit

应用范围	Immunohistochemistry (IHC)
应用备注	This antibody can be stained in formalin fixed paraffin embedded tissues after microwave treatment. The optimal dilution is 5 ug/ml, however, the dilution rate should be optimized by each laboratories.
纯化	Antigen peptide
缓冲液	Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product
贮藏	Lyophilized product, 5 years at 2 8 C : Solution, 2 years at 20 C
限制	For Research Use only

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N-Cadherin(760) (Human) antibody

概述