Product details for  PARP (Human) antibody
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PARP (Human) antibody

Overview

Antigen: PARP
Antibody Type: Polyclonal
Application: Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
Reactivity: Human, Mouse (Murine), Rat
Host: Rabbit
Quantity: 1 ml (0.2 mg/ml) (Product variants)
Price: 330,00 €   (Plus shipping costs and VAT)
Order number: ABIN150132
Availability: 7 to 10 days until shipment
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Additional Information:  PARP (Human) antibody

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Antigen PARP
Immunogen Synthetic peptide mapping to the amino terminal domain of human PARP.
Reactivity Human, Mouse (Murine), Rat
Antibody Type Polyclonal
Isotype IgG »Matching secondary antibodies
Description PARP is a 116 kDa nuclear protein which is strongly activated by DNA strand breaks. PARP plays a role in DNA repair as well as in other cellular processes, including DNA replication, cell proliferation and differentiation. During apoptosis, ICE family members, such as caspase 3 and 7, cleave PARP to yield an 85 kDa and a 25 kDa fragment. PARP cleavage is considered to be one of the classical characteristics of apoptosis.
Host Rabbit

Application Details:  PARP (Human) antibody

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Application Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
Application Notes IHC-P: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/400. Reactive with the 112 KD and 29 KD fragments. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Concentration 0.2 mg/ml
Purity Immunogen affinity purified
Buffer Preservative: 0.1% Sodium AzideConstituents: 0.2% Gelatin, PBS
Storage Store at 4 C. Aliquot and store at -20 C long-term.
Restrictions For research use only

External Information:  PARP (Human) antibody

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Google Scholar Find more references for antigen PARP on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen PARP (Bioinformatic Harvester (EMBL))