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Product details for SMRT (Human) antibody
SMRT (Human) antibody
Overview
| Antigen: | N-CoR 2 / SMRT |
| Antibody Type: | Monoclonal |
| Application: | Immunoprecipitation (IP), Western Blotting (WB), Immunoblotting (IB) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 360,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN152352 |
| Availability: | Ships in 7 to 10 days |
Additional Information: SMRT (Human) antibody
| Antigen | N-CoR 2 / SMRT |
| Immunogen | A synthetic peptide from the human SMRT protein corresponding to amino acids994-1005 (ASASDPHREKTQ) coupled to KLH. |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Format | Purified |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | Nuclear hormone receptors are transcription factors regulated by ligand binding. In theabsence of ligand there is a physical interaction between the nuclear receptors that donot interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helpstarget histone deacetylases and other components of a multiprotein repressor complexto the specific target promoter to silence gene transcription. Synonyms: NCoR 2 antibody, nuclear receptor co-repressor 2 antibody, Silencing Mediator forRetanoid and Thyroid Hormone Receptors antibody, SMRT antibody, SMRTE antibody |
| Clone | H7 |
| Host | Mouse |
| Specificity | This antibody is specific for SMRT. ABIN152352 reacts with human SMRT. |
Application Details: SMRT (Human) antibody
| Application | Immunoprecipitation (IP), Western Blotting (WB), Immunoblotting (IB) |
| Application Notes | Immunoblotting and immunoprecipitation. Clone H7 recognizes the Silencing Mediatorfor Retinoid and Thyroid receptors (SMRT) gene product, a 168 kDa nuclear protein.Suggested working dilutions: *Western Blot 1-5 ug/mlImmunoprecipitation 1-5 ug/ml*The investigator should determine the optimal working dilution for a specific application. Positive Control:HBL100 |
| Concentration | 1 mg/ml |
| Buffer | 0.1 ml (1 mg/ml) of antibody purified from hybridoma cell culture supernatant by proteinG chromatography to at least 95% homogeneity as determined by SDS-PAGE.Prepared in 10mM PBS (pH 7.4). |
| Storage | Store vial at -20 degrees Celsius,,, avoid repeated freezing and thawing |
| Restrictions | For Research Use only |
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