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Product details for TRF2 (Human) antibody
TRF2 (Human) antibody
Overview
| Antigen: | TRF2 |
| Antibody Type: | Monoclonal |
| Application: | Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 330,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN143765 |
| Availability: | 7 to 10 days until shipment |
Additional Information: TRF2 (Human) antibody
| Antigen | TRF2 |
| Immunogen | Baculovirus expressing full length TRF2 protein. |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types. |
| Clone | 4A794 |
| Host | Mouse |
Application Details: TRF2 (Human) antibody
| Application | Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | ICC: Use at an assay dependent dilution. IP: Use 2ug for 10^6 cells. WB: Use at a concentration of 2 ug/ml. Detects distinct doublet bands of approximately 66 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 0.5 mg/ml |
| Purity | Protein G purified |
| Buffer | Preservative: 0.05% Sodium AzideConstituents: 0.2% Gelatin, PBS |
| Storage | Store at 4 C. Aliquot and store at -20 C long-term. |
| Research Area | Cell Cycle, Signaling |
| Restrictions | For research use only |
External Information: TRF2 (Human) antibody
| Google Scholar | Find more references for clone 4A794 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen TRF2 (Bioinformatic Harvester (EMBL)) |
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