Product details for  TRF2 (Human) antibody
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TRF2 (Human) antibody

Overview

Antigen: TRF2
Antibody Type: Polyclonal
Application: Immunoprecipitation (IP), Western Blotting (WB)
Reactivity: Human
Host: Goat
Quantity: 100 µg (0.5 mg/ml)
Price: 349,00 €   (Plus shipping costs and VAT)
Order number: ABIN146726
Availability: 7 to 10 days until shipment
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Additional Information:  TRF2 (Human) antibody

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Antigen TRF2
Immunogen Baculovirus expressed His-tagged whole length TRF2 protein was used for immunizing goat.
Reactivity Human
Antibody Type Polyclonal
Format Liquid
Isotype IgG »Matching secondary antibodies
Description TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types.
Host Goat

Application Details:  TRF2 (Human) antibody

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Application Immunoprecipitation (IP), Western Blotting (WB)
Application Notes IP: Use 2ug for 10^6 cells. WB: Use at a concentration of 2 ug/ml. Predicted molecular weight: 60 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Concentration 0.5 mg/ml
Purity Protein G purified
Buffer Preservative: 0.02% Sodium AzideConstituents: PBS
Storage Store at 4 C. Aliquot and store at -20 C long-term.
Research Area Cell Cycle, Signaling
Restrictions For research use only

External Information:  TRF2 (Human) antibody

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Google Scholar Find more references for antigen TRF2 on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen TRF2 (Bioinformatic Harvester (EMBL))