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Product details for Thymidylate Synthase (Human) antibody
Thymidylate Synthase (Human) antibody
Overview
| Antigen: | Thymidylate Synthase |
| Antibody Type: | Polyclonal |
| Application: | ELISA, Immunofluorescence (IF), Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Antibody Purification (AP), Primary cell culture (PCC), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Sheep |
| Quantity: | |
| Price: | 197,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN142388 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Thymidylate Synthase (Human) antibody
| Antigen | Thymidylate Synthase |
| Immunogen | Recombinant human Thymidylate Synthase (36 kDa) produced in E.coli |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Polyclonal |
| Format | Liquid |
| Isotype | IgG »Matching secondary antibodies |
| Description | Because inhibition of Thymidylate Synthase (TS) prevents DNA synthesis and cell proliferation, the enzyme is an important target for cancer chemotherapeutic drugs, specifically the fluoropyrimidine group of antineoplastic drugs used to treat solid tumors. |
| Host | Sheep |
| Specificity | Detects Thymidylate Synthase by immunochemistry in proliferating cell cultures and tissues but does not stain non-proliferating cells.Normal colon mucosa shows weak staining. However, some colorectal cancer specimens show very strong staining. |
Application Details: Thymidylate Synthase (Human) antibody
| Application | ELISA, Immunofluorescence (IF), Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Antibody Purification (AP), Primary cell culture (PCC), Western Blotting (WB) |
| Application Notes | ELISA: 1:10,000 using ABIN150957 Immunoprecipitation: 1:500 (pre-clearing with a non-specific sheep IgG is helpful to reduce background)Immunofluorescence microscopy Immunohistochemistry (paraffin sections).Immunoblotting: 1:1,000-1:5,000 using ABIN150957. Reactivity in other immunoassays is unknown. |
| Concentration | 10 mg/ml |
| Purity | IgG fraction |
| Buffer | 0.02 M Potassium phosphate, 0.15 M sodium chloride, pH 7.2, containing 0.01% sodium azide |
| Storage | Keep as concentrated solution. Store at 4?C short term. For extended storage aliquot and store at -20?C or below. Avoid freeze-thaw cycles. |
| Research Area | Enzymes |
| Restrictions | For research use only |
External Information: Thymidylate Synthase (Human) antibody
| Google Scholar | Find more references for antigen Thymidylate Synthase on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Thymidylate Synthase (Bioinformatic Harvester (EMBL)) |
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