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产品详细信息： a disintegrin and metalloproteinase domain 17 (tumor necr...
a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) (Human) antibody
概述
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| 抗原: | A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) |
| 抗体类型: | 单克隆抗体 |
| 应用范围: | Immunohistochemistry (IHC), ELISA, Western Blotting (WB) |
| 目标物种: | Human |
| 抗体来源: | Mouse |
| 规格: | |
| 价格: | 396,00 € (加上增值税, €10.00干冰费用和增值税) |
| 货号: | ABIN167544 |
| 发货时间: | Delivery in 7 to 10 days |
详细信息: a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) (Human) antibody
| 抗原 | A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) |
| 基因ID | 6868 |
| 免疫原 | ADAM17 (NP_003174, 215 a.a. ~ 315 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: (without GST) RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDN AGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDV* |
| 目标物种 | Human |
| 抗体类型 | 单克隆抗体 |
| 抗体同种型 | IgG2b Kappa »相配的二抗 |
| 描述 | ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway. Mouse monoclonal antibody raised against a partial recombinant ADAM17. Synonyms: CD156b, MGC71942, TACE, cSVP |
| 克隆 | 1F6 |
| 抗体来源 | Mouse |
使用细节: a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) (Human) antibody
| 应用范围 | Immunohistochemistry (IHC), ELISA, Western Blotting (WB) |
| 应用备注 | Quality Control: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. |
| 缓冲液 | In 1x PBS, pH 7.2 Western Blot detection against Immunogen (37.11 KDa) . |
| 贮藏 | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| 限制 | For Research Use only |
图像: a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) (ADAM17) (Human) antibody
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Western Blot detection against Immunogen (37.11 KDa) .
Immunoperoxidase of monoclonal antibody to ADAM17 (H00006868-M01) on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
The detection limit for recombinant GST tagged ADAM17 is approximately 3ng/ml as a capture antibody. |
