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Product details for alpha 2 Macroglobulin (Human) antibody
alpha 2 Macroglobulin (Human) antibody
Overview
| Antigen: | Alpha 2 Macroglobulin |
| Antibody Type: | Polyclonal |
| Application: | Immunoelectrophoresis (IEP), Radioimmunoassay (RIA), Rocket Immunoelectrophoresis (IEP) |
| Reactivity: | Human, Dog (Canine), Rabbit, Bovine |
| Host: | Sheep |
| Quantity: | |
| Price: | 271,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN146931 |
| Availability: | 7 to 10 days until shipment |
Additional Information: alpha 2 Macroglobulin (Human) antibody
| Antigen | Alpha 2 Macroglobulin |
| Immunogen | Human &alpha,2-macroglobulin purified from plasma. |
| Reactivity | Human, Dog (Canine), Rabbit, Bovine |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | &alpha,2-Macroglobulin is a plasma protein, mainly synthesized in the liver. It is a tetrameric molecule, with a molecular weight of 720 kDa and usually occurs in serum at 1000-1500 mg/L. Its main function is as a protease inhibitor. Following conformational change, the protease is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites, which react with receptors on a variety of cells including macrophages and liver cells. |
| Host | Sheep |
| Specificity | This product gives a single arc when tested by IEP and 2D-IEP against human serum. Identity is confirmed by double diffusion (Ouchterlony) vs human serum and a known anti-human ??2-Macroglobulin. |
Application Details: alpha 2 Macroglobulin (Human) antibody
| Application | Immunoelectrophoresis (IEP), Radioimmunoassay (RIA), Rocket Immunoelectrophoresis (IEP) |
| Application Notes | RID and Rocket IEP: 1uL antiserum/cm?? gel vs 5uL neat-1/10 dilution human serumDouble diffusion: 10uL antiserum vs 5uL serumIEP: 100uL antiserum vs 5uL serum The use of 3% PEG 6000 with 1.2%agarose in a suitable buffer (such as TBE or Tris-barbital pH >8.2) is recommended. Suitability for use in nephelometry, immunohistochemical procedures, enzyme-linked immunosorbentassays and Western blot has not been assessed but use in such assays should not necessarily beexcluded. |
| Purity | IgG fraction |
| Buffer | Glycine buffered saline pH7.4, 0.1% Sodium Azide, 0.1% EACA, 0.01% Benzamidine,1mM EDTA |
| Storage | Store at 4 C where it will remain stable until the given expiry date. Slight precipitation can occur on storage which may be removed by centrifugation and should not affectperformance characteristics. |
| Restrictions | For research use only |
External Information: alpha 2 Macroglobulin (Human) antibody
| Google Scholar | Find more references for antigen alpha 2 Macroglobulin on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen alpha 2 Macroglobulin (Bioinformatic Harvester (EMBL)) |
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