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Antigen
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CAMP responsive element modulator (CREM)
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Gene ID
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1390
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Immunogen
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CREM (NP_853549, 201 a.a. ~ 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: (without GST) ATGDMPTYQIRAPTAALPQGVVMAASPGSLHSPQQLAEEATRKRELRLMKNREAA KECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTDY*
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Reactivity
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Human
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Antibody Type
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Monoclonal
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Isotype
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IgG1 Kappa »Matching secondary antibodies
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Description
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CAMP responsive element modulator This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. Mouse monoclonal antibody raised against a partial recombinant CREM. Synonyms: ICER, MGC111110, MGC17881, MGC41893, hCREM-2
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Clone
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3B5
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Host
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Mouse
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