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产品详细信息： c-Ret (Long Isoform) (Human) antibody
c-Ret (Long Isoform) (Human) antibody
概述
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| 抗原: | C-Ret (Long Isoform) |
| 抗体类型: | 多克隆抗体 |
| 应用范围: | Western Blotting (WB), Immunoprecipitation (IP) |
| 目标物种: | Human |
| 抗体来源: | Rabbit |
| 规格: | |
| 价格: | 315,00 € (加上运费和增值税) |
| 货号: | ABIN180120 |
| 发货时间: | 10 days until shipment |
详细信息: c-Ret (Long Isoform) (Human) antibody
| 抗原 | C-Ret (Long Isoform) |
| 免疫原 | Synthetic peptide for C-Terminal of Human c-Ret Long Isoform (ANWMLSPSAAKLMDTFDS) Purification: Affinity Purified with synthetic peptide |
| 目标物种 | Human |
| 抗体类型 | 多克隆抗体 |
| 抗体同种型 | IgG »相配的二抗 |
| 描述 | The ret proto-oncogene products (proto-Ret protein) are expressed as 150kDa and 170kDa glycoproteins in neuroblastoma cells and as 150kDa and 190kDa glycoproteins in leukemia cells. These proteins are produced from a single polypeptide of 120kDa by posttranslational glycosylation. Although expression of the ret proto-oncogene was frequently detected in human tumors such as neuroblastoma, pheochromocytoma and thyroid medullary carcinoma, its physiological function is unknown. It turned out that the extracellular domain of the proto-Ret protein contains a cadherin-related sequence that is known to be important for Ca2+-dependent homophilic binding of cadherins. The homologous sequence found in the proto-Ret protein consists of about 110 amino acids and is tandemly repeated 3 4 times in the extracellular domains of all vertebrate cadherins. The sequence of the proto-Ret protein showed 20-30% identity with the member of the cadherin superfamily in the amino acid level. This suggests that possibility that the proto-Ret protein may function as a cell adhesion molecule like cadherins. |
| 抗体来源 | Rabbit |
| 特异性 | Long Isoform specific |
使用细节: c-Ret (Long Isoform) (Human) antibody
| 应用范围 | Western Blotting (WB), Immunoprecipitation (IP) |
| 应用备注 | This antibody can be used not only for western blotting in concentration of 2-5 ug/ml but also for immunoprecipitation. |
| 纯化 | Antigen peptide |
| 缓冲液 | Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product |
| 贮藏 | Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20 |
| 限制 | For Research Use only |
外部连接: c-Ret (Long Isoform) (Human) antibody
| Google Scholar | 抗原 c-Ret (Long Isoform) |
| EMBL Harvester | 在human, mouse 或 rat 基因组里搜索抗原c-Ret (Long Isoform) (Bioinformatic Harvester (EMBL)) |
