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ERBB3 antibody (C-Term)

Name: ERBB3 antibody (C-Term)
SKU: ABIN126793
Availability: InStock

This Mouse Monoclonal antibody specifically detects ERBB3 in WB. It exhibits reactivity toward Human.

Western Blotting (WB) image for anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (C-Term) antibody (ABIN126793) (ERBB3 antibody (C-Term))

1 image

Catalog No. ABIN126793

$780.00

Plus shipping costs $50.00

0.1 mg

Shipping to: United States

Delivery in 1 to 2 Business Days

Quick Overview for ERBB3 antibody (C-Term) (ABIN126793)

Target

See all ERBB3 Antibodies

ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reactivity

Human

Host

Mouse

Clonality

Monoclonal

Conjugate

This ERBB3 antibody is un-conjugated

Application

Western Blotting (WB)

Clone

11A4

Discover our top product ERBB3 Primary Antibody

Binding Specificity
27

26

24

15

15

15

9

8

7

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

Specificity

This antibody specifically recognizes the C-terminus of erbB3 at 185 kDa.

Characteristics

Synonyms: ERBB-3, c-erbB-3, HER-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cellsurface receptor HER3, Proto-oncogene-like protein c-ErbB-3

Purification

Subsequent Thiophilic Adsorption and Size Exclusion Chromatography

Components

incl. positive Control

Immunogen

Synthetic petide conjugated to KLH.

Isotype

IgG1
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55), (N-Term) antibody
ERBB3 Reactivity: Human, Mouse WB, FACS, IHC (p) Host: Rabbit Polyclonal RB01467 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 707-964) antibody
ERBB3 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibody
ERBB3 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (C-Term) antibody
ERBB3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1-130) antibody
ERBB3 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 2E9 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55) antibody
ERBB3 Reactivity: Human, Mouse WB, IHC, ELISA, FACS Host: Rabbit Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibody
ERBB3 Reactivity: Human WB, DB Host: Rabbit Polyclonal RB25837 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (C-Term) antibody
Verified ERBB3 Reactivity: Human IHC, ELISA, IF, FACS Host: Goat Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1328) antibody
ERBB3 Reactivity: Human, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 661-760) antibody
ERBB3 Reactivity: Human, Mouse, Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Application Notes

Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Reconstitution

Restore with 1 mL H2O (15 min, RT)

Buffer

1 mLPBS, 0.09 % Sodium Azide, PEG and Sucrose

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C/-80 °C

Storage Comment

Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch.

Expiry Date

12 months
Target

ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Alternative Name

ERBB3 / HER3

Background

ErbB3 is a member of the EGFR/erbB receptor tyrosine kinase family. ErbB3 lacks intrinsic kinase activity due to an amino acid substitution within the ATP binding site. Upon heterodimerization with the other erbB family members, erbB3 becomes phosphorylated at multiple tyrosine residues that represent docking sites for downstream signaling proteins, e.g. PI3K, grb7 and shc. The erbB3 cytoplasmic domain contains 6 docking sites for PI3K. Thus, erbB3 is a potent activator of the PI3K/PKB signaling pathway.Synonyms: ERBB-3, HER-3, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, c-erbB-3

Molecular Weight

185 kDa

Gene ID

2065

UniProt

P21860

Pathways

RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway