Product details for  C-erbB-3 / Her-3 (Human) antibody
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C-erbB-3 / Her-3 (Human) antibody

Overview

Antigen:
Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunoprecipitation (IP)
Reactivity: Human
Host: Rabbit
Quantity: 0.2 mg (1 mg/ml)
Price: 330,00 €   (Plus shipping costs and VAT)
Order number: ABIN121069
Availability: Ships in 3 to 10 days
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Additional Information:  C-erbB-3 / Her-3 (Human) antibody

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Antigen
Immunogen Synthetic Peptide: E(1004) L E P E L D L D L D L E(1016).
Reactivity Human
Antibody Type
Format Purified
Isotype IgG1 »Matching secondary antibodies
Host Rabbit
Specificity Her-3, also known as c-erbB-3, is a Type 1 membrane protein found in numerous cell types. It is a member of the EGF receptor protein family, and is activated by neuregulins and NTAK. Her-3 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies. Her-3 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself. ABIN121069 detects Her-3 from human samples. ABIN121069 has been successfully used in immunoprecipitation, immunohistochemical, immunofluorescence and ELISA procedures. By immunoprecipitation, this antibody detects ~185 kDa protein, representing Her-3 from human tissue extracts.This antibody has also been used in immunohistochemical, immunofluorescence and ELISA procedures using human tissues. ABIN121069 immunizing peptide corresponds to amino acid residues 1004 to 1016 of human cytoplasmic domain of HER-3 protein.

Application Details:  C-erbB-3 / Her-3 (Human) antibody

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Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunoprecipitation (IP)
Application Notes Immunoprecipitation. ELISA. Immunofluorescence: 10ug/ml. Immunohistochemistry: 6 – 8 ug/ml. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 1 mg/ml
Buffer This antibody is supplied as liquid, protein G purified IgG1 in PBS with 1 mg/ml BSA and 0.05% sodium azide as preservative.
Storage Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Receptors, Growth Factors
Restrictions Research only

External Information:  C-erbB-3 / Her-3 (Human) antibody

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