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产品详细信息： c-kit (12A8) (Human) antibody
c-kit (12A8) (Human) antibody
概述
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| 抗原: | C-kit (12A8) |
| 抗体类型: | 单克隆抗体 |
| 应用范围: | Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Neutralizing (Neut) |
| 目标物种: | Human |
| 抗体来源: | Mouse |
| 规格: | |
| 价格: | 315,00 € (加上运费和增值税) |
| 货号: | ABIN180067 |
| 发货时间: | 10 days until shipment |
详细信息: c-kit (12A8) (Human) antibody
| 抗原 | C-kit (12A8) |
| 免疫原 | Recombinant protein of extracellular domain of human c-Kit |
| 目标物种 | Human |
| 抗体类型 | 单克隆抗体 |
| 抗体同种型 | IgG1 »相配的二抗 |
| 描述 | The proto-oncogene c-kit encodes a transmembrane tyrosine kinase receptor, and its ligand for c-Kit receptor has been identified as the stem cell factor (SCF). Recent experimental studies have shown that c-Kit plays a key role in the development of a component of the pacemaker system that is required for generation of autonomic gut motility. These studies further suggest that interaction of the c-Kit and SCF is essential for development of enteric nervous system. Recently, it is reported that the c-Kit may be an important marker for gastrointestinal stromal tumors (GISTs) which may originate from the interstitial cells of Cajal (ICCs). This monoclonal antibody recognizes c-Kit by W.B. and I.P. applications and it enables FACS analysis of c-Kit-expressing cells. It has been confirmed that the addition of this antibody does not induce ligand-binding-dependent phosphorylation of c-Kit and it may be used as a neutralizing antibody. |
| 克隆 | 12A8 |
| 抗体来源 | Mouse |
| 特异性 | Confirmed by western blotting with SY cell. |
使用细节: c-kit (12A8) (Human) antibody
| 应用范围 | Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Neutralizing (Neut) |
| 应用备注 | This antibody can be used for western blotting at 1-5 ug/mL. This antibody can be used for immunoprecipitation at 3-5 ug/mL. |
| 纯化 | Protein A |
| 缓冲液 | Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1.0 mL deionized water will be added to the product |
| 贮藏 | Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20 |
| 研究领域 | Proliferation Markers |
| 限制 | For Research Use only |
