Product details for gamma Tubulin-Centrosome Marker (Human) antibody
gamma Tubulin-Centrosome Marker (Human) antibody
Overview
| Antigen: | Gamma Tubulin-Centrosome Marker |
| Antibody Type: | Monoclonal |
| Application: | ELISA, Immunohistochemistry (IHC), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat, Dog (Canine), Bovine, Hamster |
| Host: | Mouse |
| Quantity: | |
| Price: | 271,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN144791 |
| Availability: | 7 to 10 days until shipment |
Additional Information: gamma Tubulin-Centrosome Marker (Human) antibody
| Antigen | Gamma Tubulin-Centrosome Marker |
| Immunogen | Synthetic peptide conjugated to KLH, corresponding to N-terminal amino acids 38-53 of gamma Tubulin. |
| Reactivity | Human, Mouse (Murine), Rat, Dog (Canine), Bovine, Hamster |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | The protein that binds microtubule minus ends and is responsible for mediating the link between microtubules and the centrosome is called gamma tubulin. Gamma Tubulin functions as the microtubule nucleator at the microtubule organizing centre (MTOC). By binding to the beta tubulin half of the tubulin molecule, it establishes the polarity of a microtubule, leaving the alpha tubulin half exposed at the positive end. Gamma Tubulin (approx. 48 kD) is a ubiquitous and highly conserved protein within the MTOCs in eukaryotic kingdom. It is related to alpha and beta tubulin and is, thus, a member of the tubulin superfamily of proteins. However, its abundance is less than 1% of the level of either alpha or beta tubulin. Moreover, unlike alpha and beta tubulin, it is not a component of microtubules. Rather, it is located at the MTOC. gamma Tubulin shares approximately 28-32% identity with alpha tubulin from various organisms and 32-36% identity with beta tubulins. The detection, localization |
| Clone | GTU-88 |
| Host | Mouse |
Application Details: gamma Tubulin-Centrosome Marker (Human) antibody
| Application | ELISA, Immunohistochemistry (IHC), Western Blotting (WB) |
| Application Notes | ELISA: Use at an assay dependent dilution. IHC: Use at an assay dependent dilution. WB: Use at a dilution of 1/10000. This concentration was determined using cultured chicken fibroblasts extract. Detects a band of approximately 48 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Purity | Ascites |
| Buffer | Preservative: 15mM Sodium AzideConstituents: Ascites fluid |
| Restrictions | For research use only |
External Information: gamma Tubulin-Centrosome Marker (Human) antibody
| Google Scholar | Find more references for clone GTU-88 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen gamma Tubulin-Centrosome Marker (Bioinformatic Harvester (EMBL)) |







